The parish of St. Ann’s was founded in 1707, The interior of the church was designed by Isaac Wills and completed in 1720. The original, partially completed facade was replaced by the present imposing neo-Romanesque structure by Sir Thomas Dean in 1868.

During the 17th century, members of the Royal family, Crown officials, & local gentry were regular attendants. The widely known author of Dracula - Bram Stoker, married there in 1878